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Host factor prioritization for pan-viral genetic perturbation screens using random intercept models and network propagation

Genetic perturbation screens using RNA interference (RNAi) have been conducted successfully to identify host factors that are essential for the life cycle of bacteria or viruses. So far, most published studies identified host factors primarily for single pathogens. Furthermore, often only a small su...

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Detalles Bibliográficos
Autores principales: Dirmeier, Simon, Dächert, Christopher, van Hemert, Martijn, Tas, Ali, Ogando, Natacha S., van Kuppeveld, Frank, Bartenschlager, Ralf, Kaderali, Lars, Binder, Marco, Beerenwinkel, Niko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034926/
https://www.ncbi.nlm.nih.gov/pubmed/32040506
http://dx.doi.org/10.1371/journal.pcbi.1007587