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Host factor prioritization for pan-viral genetic perturbation screens using random intercept models and network propagation
Genetic perturbation screens using RNA interference (RNAi) have been conducted successfully to identify host factors that are essential for the life cycle of bacteria or viruses. So far, most published studies identified host factors primarily for single pathogens. Furthermore, often only a small su...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034926/ https://www.ncbi.nlm.nih.gov/pubmed/32040506 http://dx.doi.org/10.1371/journal.pcbi.1007587 |