Intrinsic disorder controls two functionally distinct dimers of the master transcription factor PU.1

Transcription factors comprise a major reservoir of conformational disorder in the eukaryotic proteome. The hematopoietic master regulator PU.1 presents a well-defined model of the most common configuration of intrinsically disordered regions (IDRs) in transcription factors. We report that the struc...

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Detalles Bibliográficos
Autores principales: Xhani, Suela, Lee, Sangchoon, Kim, Hye Mi, Wang, Siming, Esaki, Shingo, Ha, Van L. T., Khanezarrin, Mahtab, Fernandez, Giselle L., Albrecht, Amanda V., Aramini, James M., Germann, Markus W., Poon, Gregory M. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034988/
https://www.ncbi.nlm.nih.gov/pubmed/32128405
http://dx.doi.org/10.1126/sciadv.aay3178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034988/
https://www.ncbi.nlm.nih.gov/pubmed/32128405
http://dx.doi.org/10.1126/sciadv.aay3178

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