In vitro Transport Ability of ABCC2 (G1249A) Polymorphic Variant Towards Anticancer Drugs

OBJECTIVE: Multidrug resistance-associated protein 2 (MRP2), encoded by ABCC2 gene, is involved in the efflux of certain anticancer drugs. Here we observed whether the ABCC2 (G1249A) polymorphism impacts the transport abilities of MRP2-dependent paclitaxel, docetaxel, and doxorubicin in recombinant...

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Detalles Bibliográficos
Autores principales: Lian, Guo, Yuan, Jia, Gao, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035141/
https://www.ncbi.nlm.nih.gov/pubmed/32110040
http://dx.doi.org/10.2147/OTT.S207613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035141/
https://www.ncbi.nlm.nih.gov/pubmed/32110040
http://dx.doi.org/10.2147/OTT.S207613

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