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In vitro Transport Ability of ABCC2 (G1249A) Polymorphic Variant Towards Anticancer Drugs
OBJECTIVE: Multidrug resistance-associated protein 2 (MRP2), encoded by ABCC2 gene, is involved in the efflux of certain anticancer drugs. Here we observed whether the ABCC2 (G1249A) polymorphism impacts the transport abilities of MRP2-dependent paclitaxel, docetaxel, and doxorubicin in recombinant...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035141/ https://www.ncbi.nlm.nih.gov/pubmed/32110040 http://dx.doi.org/10.2147/OTT.S207613 |