ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer’s disease

Mid-life hypertension and cerebrovascular dysfunction are associated with increased risk of later life dementia, including Alzheimer’s disease (AD). The classical renin–angiotensin system (cRAS), a physiological regulator of blood pressure, functions independently within the brain and is overactive...

Descripción completa

Detalles Bibliográficos
Autores principales: Evans, Charles E., Miners, James S., Piva, Giulia, Willis, Christine L., Heard, David M., Kidd, Emma J., Good, Mark A., Kehoe, Patrick G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035243/
https://www.ncbi.nlm.nih.gov/pubmed/31982938
http://dx.doi.org/10.1007/s00401-019-02098-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035243/
https://www.ncbi.nlm.nih.gov/pubmed/31982938
http://dx.doi.org/10.1007/s00401-019-02098-6

Ejemplares similares