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ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer’s disease

Mid-life hypertension and cerebrovascular dysfunction are associated with increased risk of later life dementia, including Alzheimer’s disease (AD). The classical renin–angiotensin system (cRAS), a physiological regulator of blood pressure, functions independently within the brain and is overactive...

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Detalles Bibliográficos
Autores principales:	Evans, Charles E., Miners, James S., Piva, Giulia, Willis, Christine L., Heard, David M., Kidd, Emma J., Good, Mark A., Kehoe, Patrick G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2020
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035243/ https://www.ncbi.nlm.nih.gov/pubmed/31982938 http://dx.doi.org/10.1007/s00401-019-02098-6

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