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Investigating cone photoreceptor development using patient-derived NRL null retinal organoids

Photoreceptor loss is a leading cause of blindness, but mechanisms underlying photoreceptor degeneration are not well understood. Treatment strategies would benefit from improved understanding of gene-expression patterns directing photoreceptor development, as many genes are implicated in both devel...

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Detalles Bibliográficos
Autores principales: Kallman, Alyssa, Capowski, Elizabeth E., Wang, Jie, Kaushik, Aniruddha M., Jansen, Alex D., Edwards, Kimberly L., Chen, Liben, Berlinicke, Cynthia A., Joseph Phillips, M., Pierce, Eric A., Qian, Jiang, Wang, Tza-Huei, Gamm, David M., Zack, Donald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035245/
https://www.ncbi.nlm.nih.gov/pubmed/32081919
http://dx.doi.org/10.1038/s42003-020-0808-5