Three-dimensional culture models mimic colon cancer heterogeneity induced by different microenvironments

Colorectal cancer demonstrates intra-tumour heterogeneity formed by a hierarchical structure comprised of cancer stem cells (CSCs) and their differentiated progenies. The mechanism by which CSCs are maintained and differentiated needs to be further elucidated, and there is evidence that the tumour m...

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Detalles Bibliográficos
Autores principales: Kawai, Shigeto, Yamazaki, Masaki, Shibuya, Keita, Yamazaki, Masaya, Fujii, Etsuko, Nakano, Kiyotaka, Suzuki, Masami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035265/
https://www.ncbi.nlm.nih.gov/pubmed/32081957
http://dx.doi.org/10.1038/s41598-020-60145-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035265/
https://www.ncbi.nlm.nih.gov/pubmed/32081957
http://dx.doi.org/10.1038/s41598-020-60145-9

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