Abrogation of type-I interferon signalling alters the microglial response to Aβ(1–42)

Neuroinflammation and accompanying microglial dysfunction are now appreciated to be involved in Alzheimer’s disease (AD) pathogenesis. Critical to the process of neuroinflammation are the type-I interferon (IFN) family of cytokines. Efforts to phenotypically characterize microglia within AD identify...

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Detalles Bibliográficos
Autores principales: Moore, Zachery, Mobilio, Frank, Walker, Frederick R., Taylor, Juliet M., Crack, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035268/
https://www.ncbi.nlm.nih.gov/pubmed/32081950
http://dx.doi.org/10.1038/s41598-020-59917-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035268/
https://www.ncbi.nlm.nih.gov/pubmed/32081950
http://dx.doi.org/10.1038/s41598-020-59917-0

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