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Structural ensemble of a glutamate transporter homologue in lipid nanodisc environment

Glutamate transporters are cation-coupled secondary active membrane transporters that clear the neurotransmitter L-glutamate from the synaptic cleft. These transporters are homotrimers, with each protomer functioning independently by an elevator-type mechanism, in which a mobile transport domain alt...

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Detalles Bibliográficos
Autores principales: Arkhipova, Valentina, Guskov, Albert, Slotboom, Dirk J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035293/
https://www.ncbi.nlm.nih.gov/pubmed/32081874
http://dx.doi.org/10.1038/s41467-020-14834-8