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Structure of the human cation–chloride cotransporter NKCC1 determined by single-particle electron cryo-microscopy

The secondary active cation–chloride cotransporters (CCCs) utilize the existing Na(+) and/or K(+) gradients to move Cl(−) into or out of cells. NKCC1 is an intensively studied member of the CCC family and plays fundamental roles in regulating trans-epithelial ion movement, cell volume, chloride home...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoyong, Wang, Qinzhe, Cao, Erhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035313/
https://www.ncbi.nlm.nih.gov/pubmed/32081947
http://dx.doi.org/10.1038/s41467-020-14790-3