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Binding of the periplakin linker requires vimentin acidic residues D176 and E187

Plakin proteins form connections that link the cell membrane to the intermediate filament cytoskeleton. Their interactions are mediated by a highly conserved linker domain through an unresolved mechanism. Here analysis of the human periplakin linker domain structure reveals a bi-lobed module transec...

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Detalles Bibliográficos
Autores principales: Odintsova, Elena, Mohammed, Fiyaz, Trieber, Catharine, Rodriguez-Zamora, Penelope, Al-Jassar, Caezar, Huang, Tzu-Han, Fogl, Claudia, Knowles, Timothy, Sridhar, Pooja, Kumar, Jitendra, Jeeves, Mark, Chidgey, Martyn, Overduin, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035337/
https://www.ncbi.nlm.nih.gov/pubmed/32081916
http://dx.doi.org/10.1038/s42003-020-0810-y