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Klf5 acetylation regulates luminal differentiation of basal progenitors in prostate development and regeneration

Prostate development depends on balanced cell proliferation and differentiation, and acetylated KLF5 is known to alter epithelial proliferation. It remains elusive whether post-translational modifications of transcription factors can differentially determine adult stem/progenitor cell fate. Here we...

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Detalles Bibliográficos
Autores principales: Zhang, Baotong, Ci, Xinpei, Tao, Ran, Ni, Jianping Jenny, Xuan, Xiaoyan, King, Jamie L., Xia, Siyuan, Li, Yixiang, Frierson, Henry F., Lee, Dong-Kee, Xu, Jianming, Osunkoya, Adeboye O., Dong, Jin-Tang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035357/
https://www.ncbi.nlm.nih.gov/pubmed/32081850
http://dx.doi.org/10.1038/s41467-020-14737-8