Systematic Administration of B Vitamins Alleviates Diabetic Pain and Inhibits Associated Expression of P2X3 and TRPV1 in Dorsal Root Ganglion Neurons and Proinflammatory Cytokines in Spinal Cord in Rats

BACKGROUND: Treatment of diabetic neuropathic pain (DNP) continues to be a major challenge, and underlying mechanisms of DNP remain elusive. We investigated treatment effects of B vitamins on DPN- and DNP-associated alterations of neurochemical signaling in the nociceptive dorsal root ganglion (DRG)...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Duan-Duan, Gao, Yu, Wang, Shan, Xie, Zhong, Song, Xue-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035549/
https://www.ncbi.nlm.nih.gov/pubmed/32104520
http://dx.doi.org/10.1155/2020/3740162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035549/
https://www.ncbi.nlm.nih.gov/pubmed/32104520
http://dx.doi.org/10.1155/2020/3740162

Ejemplares similares