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Novel Fluorescent Mitochondria-Targeted Probe MitoCLox Reports Lipid Peroxidation in Response to Oxidative Stress In Vivo

A new mitochondria-targeted probe MitoCLox was designed as a starting compound for a series of probes sensitive to cardiolipin (CL) peroxidation. Fluorescence microscopy reported selective accumulation of MitoCLox in mitochondria of diverse living cell cultures and its oxidation under stress conditi...

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Detalles Bibliográficos
Autores principales: Lyamzaev, Konstantin G., Panteleeva, Alisa A., Karpukhina, Anna A., Galkin, Ivan I., Popova, Ekatherina N., Pletjushkina, Olga Yu., Rieger, Bettina, Busch, Karin B., Mulkidjanian, Armen Y., Chernyak, Boris V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035557/
https://www.ncbi.nlm.nih.gov/pubmed/32104531
http://dx.doi.org/10.1155/2020/3631272