Paeonol Attenuates Methotrexate-Induced Cardiac Toxicity in Rats by Inhibiting Oxidative Stress and Suppressing TLR4-Induced NF-κB Inflammatory Pathway

Methotrexate (MTX) is a commonly used chemotherapeutic agent. Oxidative stress and inflammation have been proved in the development of MTX toxicity. Paeonol is a natural phenolic compound with various pharmacological activities including antioxidant and anti-inflammatory properties. The aim of the p...

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Detalles Bibliográficos
Autores principales: Al-Taher, Abdulla Y., Morsy, Mohamed A., Rifaai, Rehab A., Zenhom, Nagwa M., Abdel-Gaber, Seham A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035561/
https://www.ncbi.nlm.nih.gov/pubmed/32104151
http://dx.doi.org/10.1155/2020/8641026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035561/
https://www.ncbi.nlm.nih.gov/pubmed/32104151
http://dx.doi.org/10.1155/2020/8641026

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