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Paeonol Attenuates Methotrexate-Induced Cardiac Toxicity in Rats by Inhibiting Oxidative Stress and Suppressing TLR4-Induced NF-κB Inflammatory Pathway
Methotrexate (MTX) is a commonly used chemotherapeutic agent. Oxidative stress and inflammation have been proved in the development of MTX toxicity. Paeonol is a natural phenolic compound with various pharmacological activities including antioxidant and anti-inflammatory properties. The aim of the p...
Autores principales: | Al-Taher, Abdulla Y., Morsy, Mohamed A., Rifaai, Rehab A., Zenhom, Nagwa M., Abdel-Gaber, Seham A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035561/ https://www.ncbi.nlm.nih.gov/pubmed/32104151 http://dx.doi.org/10.1155/2020/8641026 |
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