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Chloroquine and Rapamycin Augment Interleukin-37 Expression via the LC3, ERK, and AP-1 Axis in the Presence of Lipopolysaccharides

IL-37 is a cytokine that plays critical protective roles in many metabolic inflammatory diseases, and its therapeutic potential has been confirmed by exogenous IL-37 administration. However, its regulatory mechanisms remain unclear. U937 cells were treated with autophagy-modifying reagents (3-MA, ch...

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Detalles Bibliográficos
Autores principales: Shi, Xiaoyi, Lai, Chunhui, Zhao, Lianyu, Zhang, Mingying, Liu, Xi, Peng, Shanqin, Guo, Weizhong, Xu, Qiuying, Chen, Song, Chen, Guang-xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035573/
https://www.ncbi.nlm.nih.gov/pubmed/32104716
http://dx.doi.org/10.1155/2020/6457879