Cargando…

Combining microenvironment normalization strategies to improve cancer immunotherapy

Advances in immunotherapy have revolutionized the treatment of multiple cancers. Unfortunately, tumors usually have impaired blood perfusion, which limits the delivery of therapeutics and cytotoxic immune cells to tumors and also results in hypoxia—a hallmark of the abnormal tumor microenvironment (...

Descripción completa

Detalles Bibliográficos
Autores principales: Mpekris, Fotios, Voutouri, Chrysovalantis, Baish, James W., Duda, Dan G., Munn, Lance L., Stylianopoulos, Triantafyllos, Jain, Rakesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035612/
https://www.ncbi.nlm.nih.gov/pubmed/32015113
http://dx.doi.org/10.1073/pnas.1919764117