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TIP5 primes prostate luminal cells for the oncogenic transformation mediated by PTEN-loss

Prostate cancer (PCa) is the second leading cause of cancer death in men. Its clinical and molecular heterogeneities and the lack of in vitro models outline the complexity of PCa in the clinical and research settings. We established an in vitro mouse PCa model based on organoid technology that takes...

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Detalles Bibliográficos
Autores principales: Pietrzak, Karolina, Kuzyakiv, Rostyslav, Simon, Ronald, Bolis, Marco, Bär, Dominik, Aprigliano, Rossana, Theurillat, Jean-Philippe, Sauter, Guido, Santoro, Raffaella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035629/
https://www.ncbi.nlm.nih.gov/pubmed/32024754
http://dx.doi.org/10.1073/pnas.1911673117