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TIP5 primes prostate luminal cells for the oncogenic transformation mediated by PTEN-loss
Prostate cancer (PCa) is the second leading cause of cancer death in men. Its clinical and molecular heterogeneities and the lack of in vitro models outline the complexity of PCa in the clinical and research settings. We established an in vitro mouse PCa model based on organoid technology that takes...
Autores principales: | Pietrzak, Karolina, Kuzyakiv, Rostyslav, Simon, Ronald, Bolis, Marco, Bär, Dominik, Aprigliano, Rossana, Theurillat, Jean-Philippe, Sauter, Guido, Santoro, Raffaella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035629/ https://www.ncbi.nlm.nih.gov/pubmed/32024754 http://dx.doi.org/10.1073/pnas.1911673117 |
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