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Evaluation of in vitro antileishmanial efficacy of cyclosporin A and its non-immunosuppressive derivative, dihydrocyclosporin A

BACKGROUND: New therapeutic drugs are urgently needed against visceral leishmaniasis because current drugs, such as pentavalent antimonials and miltefosine, produce severe side effects and development of resistance. Whether cyclosporine A (CsA) and its derivatives can be used as therapeutic drugs fo...

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Detalles Bibliográficos
Autores principales: Zheng, Zhi-Wan, Li, Jiao, Chen, Han, He, Jin-Lei, Chen, Qi-Wei, Zhang, Jian-Hui, Zhou, Qi, Chen, Da-Li, Chen, Jian-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035640/
https://www.ncbi.nlm.nih.gov/pubmed/32085719
http://dx.doi.org/10.1186/s13071-020-3958-x