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Integrative analysis of breast cancer profiles in TCGA by TNBC subgrouping reveals novel microRNA-specific clusters, including miR-17-92a, distinguishing basal-like 1 and basal-like 2 TNBC subtypes

BACKGROUND: The term triple-negative breast cancer (TNBC) is used to describe breast cancers without expression of estrogen receptor, progesterone receptor or HER2 amplification. To advance targeted treatment options for TNBC, it is critical that the subtypes within this classification be described...

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Detalles Bibliográficos
Autores principales: Kalecky, Karel, Modisette, Rebecca, Pena, Samantha, Cho, Young-Rae, Taube, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035760/
https://www.ncbi.nlm.nih.gov/pubmed/32085745
http://dx.doi.org/10.1186/s12885-020-6600-6