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Alteration in Expression of miR-32 and FBXW7 Tumor Suppressor in Plasma Samples of Patients with T-cell Acute Lymphoblastic Leukemia

BACKGROUND: T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive and malignant neoplasm that arises from the hematopoietic T-cell precursors. Inactivation of FBXW7 gene is frequently observed in T-cell acute lymphoblastic leukemia, suggesting a significant tumor-suppressive role for FBXW7 in...

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Detalles Bibliográficos
Autores principales: Mansouri, Sanaz, Khansarinejad, Behzad, Mosayebi, Ghasem, Eghbali, Aziz, Mondanizadeh, Mahdieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035948/
https://www.ncbi.nlm.nih.gov/pubmed/32110099
http://dx.doi.org/10.2147/CMAR.S238470