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Allosteric mechanism for site-specific ubiquitination of FANCD2

DNA damage repair is implemented by proteins that are coordinated by specialised molecular signals. One such signal in the Fanconi Anemia (FA) DNA-interstrand crosslink repair pathway is the site-specific monoubiquitination of FANCD2 and FANCI. The signal is mediated by a multi-protein FA core compl...

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Detalles Bibliográficos
Autores principales:	Chaugule, Viduth K., Arkinson, Connor, Rennie, Martin L., Kämäräinen, Outi, Toth, Rachel, Walden, Helen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035956/ https://www.ncbi.nlm.nih.gov/pubmed/31873223 http://dx.doi.org/10.1038/s41589-019-0426-z

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