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Magnesium Sulfate Inhibits Inflammation Through P2X7 Receptors In Human Umbilical Vein Endothelial Cells

INTRODUCTION: Magnesium sulfate (MgSO(4)) is utilized for fetal neuroprotection in preterm birth but its mechanism of action is still poorly understood. P2X7 receptor (P2X7R) is required for secretion of IL-1β, and can be blocked by divalent cations such as magnesium (Mg) and its own antagonist, Bri...

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Detalles Bibliográficos
Autores principales: Ozen, Maide, Xie, Han, Shin, Na, Yousif, Ghada Al, Clemens, Julia, McLane, Michael W., Lei, Jun, Burd, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035964/
https://www.ncbi.nlm.nih.gov/pubmed/31493768
http://dx.doi.org/10.1038/s41390-019-0557-7