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Magnesium Sulfate Inhibits Inflammation Through P2X7 Receptors In Human Umbilical Vein Endothelial Cells
INTRODUCTION: Magnesium sulfate (MgSO(4)) is utilized for fetal neuroprotection in preterm birth but its mechanism of action is still poorly understood. P2X7 receptor (P2X7R) is required for secretion of IL-1β, and can be blocked by divalent cations such as magnesium (Mg) and its own antagonist, Bri...
Autores principales: | Ozen, Maide, Xie, Han, Shin, Na, Yousif, Ghada Al, Clemens, Julia, McLane, Michael W., Lei, Jun, Burd, Irina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035964/ https://www.ncbi.nlm.nih.gov/pubmed/31493768 http://dx.doi.org/10.1038/s41390-019-0557-7 |
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