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The developing gut-lung axis: post-natal growth restriction, intestinal dysbiosis and pulmonary hypertension in a rodent model

BACKGROUND: Post-natal growth restriction (PNGR) in premature infants increases risk of pulmonary hypertension (PH). In a rodent model, PNGR causes PH, while combining PNGR and hyperoxia increases PH severity. We hypothesized that PNGR causes intestinal dysbiosis and that treatment with a probiotic...

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Detalles Bibliográficos
Autores principales: Wedgwood, Stephen, Warford, Cris, Agvatisiri, Sharleen R., Thai, Phung N., Chiamvimonvat, Nipavan, Kalanetra, Karen M., Lakshminrusimha, Satyan, Steinhorn, Robin H., Mills, David A., Underwood, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035999/
https://www.ncbi.nlm.nih.gov/pubmed/31537010
http://dx.doi.org/10.1038/s41390-019-0578-2