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Context-dependent activation of SIRT3 is necessary for anchorage-independent survival and metastasis of ovarian cancer cells

Tumor cells must alter their antioxidant capacity for maximal metastatic potential. Yet the antioxidant adaptations required for ovarian cancer transcoelomic metastasis, which is the passive dissemination of cells in the peritoneal cavity, remain largely unexplored. Somewhat contradicting the need f...

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Detalles Bibliográficos
Autores principales: Kim, Yeon Soo, Vallur, Piyushi Gupta, Jones, Victoria M., Worley, Beth L., Shimko, Sara, Shin, Dong-Hui, Crawford, LaTaijah C., Chen, Chi-Wei, Aird, Katherine M., Abraham, Thomas, Shepherd, Trevor G., Warrick, Joshua I., Lee, Nam Y., Phaeton, Rebecca, Mythreye, Karthikeyan, Hempel, Nadine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036012/
https://www.ncbi.nlm.nih.gov/pubmed/31723239
http://dx.doi.org/10.1038/s41388-019-1097-7