Evaluation of the bioequivalence and food effect on the bioavailability of CC-486 (oral azacitidine) tablets in adult patients with cancer

PURPOSE: CC-486 is an oral formulation of azacitidine that allows for extended dosing schedules to prolong azacitidine exposure to malignant cells and maximize clinical activity. CC-486 300 mg daily, administered for 14 or 21 days of 28-day treatment cycles, is currently under investigation in two o...

Descripción completa

Detalles Bibliográficos
Autores principales: Babiker, Hani M., Milhem, Mohammed, Aisner, Joseph, Edenfield, William, Shepard, Dale, Savona, Michael, Iyer, Swaminathan, Abdelrahim, Maen, Beach, C. L., Skikne, Barry, Laille, Eric, Tsai, Kao-Tai, Ho, Thai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036073/
https://www.ncbi.nlm.nih.gov/pubmed/32036412
http://dx.doi.org/10.1007/s00280-020-04037-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036073/
https://www.ncbi.nlm.nih.gov/pubmed/32036412
http://dx.doi.org/10.1007/s00280-020-04037-9

Ejemplares similares