Exploration of metformin as novel therapy for osteoarthritis: preventing cartilage degeneration and reducing pain behavior

BACKGROUND: Metformin could activate adenosine monophosphate-activated protein kinase (AMPK) which was postulated as a potential therapeutic target for osteoarthritis. This study aimed to examine the effects of metformin on cartilage and pain in osteoarthritis mouse model. METHODS: Eighty 10-week-ol...

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Detalles Bibliográficos
Autores principales: Li, Hui, Ding, Xiang, Terkeltaub, Robert, Lin, Hang, Zhang, Yuqing, Zhou, Bin, He, Ke, Li, Kun, Liu, Zhichen, Wei, Jie, Yang, Yuanheng, Xie, Hui, Zeng, Chao, Lei, Guanghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036179/
https://www.ncbi.nlm.nih.gov/pubmed/32087740
http://dx.doi.org/10.1186/s13075-020-2129-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036179/
https://www.ncbi.nlm.nih.gov/pubmed/32087740
http://dx.doi.org/10.1186/s13075-020-2129-y

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