Phenotypic adaptations of Leishmania donovani to recurrent miltefosine exposure and impact on sand fly infection

BACKGROUND: Since the introduction of miltefosine (MIL) as first-line therapy in the kala-azar elimination programme in the Indian subcontinent, treatment failure rates have been increasing. Since parasite infectivity and virulence may become altered upon treatment relapse, this laboratory study ass...

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Detalles Bibliográficos
Autores principales: Hendrickx, Sarah, Van Bockstal, Lieselotte, Bulté, Dimitri, Mondelaers, Annelies, Aslan, Hamide, Rivas, Luis, Maes, Louis, Caljon, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036194/
https://www.ncbi.nlm.nih.gov/pubmed/32087758
http://dx.doi.org/10.1186/s13071-020-3972-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036194/
https://www.ncbi.nlm.nih.gov/pubmed/32087758
http://dx.doi.org/10.1186/s13071-020-3972-z

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