A single ultrasensitive assay for detection and discrimination of tau aggregates of Alzheimer and Pick diseases

Multiple neurodegenerative diseases are characterized by aggregation of tau molecules. Adult humans express six isoforms of tau that contain either 3 or 4 microtubule binding repeats (3R or 4R tau). Different diseases involve preferential aggregation of 3R (e.g Pick disease), 4R (e.g. progressive su...

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Detalles Bibliográficos
Autores principales: Metrick, Michael A., Ferreira, Natália do Carmo, Saijo, Eri, Kraus, Allison, Newell, Kathy, Zanusso, Gianluigi, Vendruscolo, Michele, Ghetti, Bernardino, Caughey, Byron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036215/
https://www.ncbi.nlm.nih.gov/pubmed/32087764
http://dx.doi.org/10.1186/s40478-020-0887-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036215/
https://www.ncbi.nlm.nih.gov/pubmed/32087764
http://dx.doi.org/10.1186/s40478-020-0887-z

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