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Inferring B cell specificity for vaccines using a Bayesian mixture model

BACKGROUND: Vaccines have greatly reduced the burden of infectious disease, ranking in their impact on global health second only after clean water. Most vaccines confer protection by the production of antibodies with binding affinity for the antigen, which is the main effector function of B cells. T...

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Detalles Bibliográficos
Autores principales: Fowler, Anna, Galson, Jacob D., Trück, Johannes, Kelly, Dominic F., Lunter, Gerton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036227/
https://www.ncbi.nlm.nih.gov/pubmed/32087698
http://dx.doi.org/10.1186/s12864-020-6571-7