Single nucleotide polymorphism of MTHFR rs1801133 associated with elevated Hcy levels affects susceptibility to cerebral small vessel disease

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) is indispensable for the conversion of homocysteine (Hcy) to methionine. The single nucleotide polymorphism (SNP) of MTHFR gene (rs1801133, C667T) is correlated with decreased enzyme activity that eventually results in elevated plasma Hcy level...

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Detalles Bibliográficos
Autores principales: Yuan, Hongyu, Fu, Man, Yang, Xianzhang, Huang, Kun, Ren, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036271/
https://www.ncbi.nlm.nih.gov/pubmed/32117640
http://dx.doi.org/10.7717/peerj.8627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036271/
https://www.ncbi.nlm.nih.gov/pubmed/32117640
http://dx.doi.org/10.7717/peerj.8627

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