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Rotation tracking of genome-processing enzymes using DNA origami rotors

Many genome-processing reactions, such as transcription, replication and repair, generate DNA rotation. Methods that directly measure DNA rotation, including rotor bead tracking(1–3), angular optical trap(4), and magnetic tweezers(5) have helped unravel the action mechanisms of a range of genome-pro...

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Detalles Bibliográficos
Autores principales: Kosuri, Pallav, Altheimer, Benjamin D., Dai, Mingjie, Yin, Peng, Zhuang, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036295/
https://www.ncbi.nlm.nih.gov/pubmed/31316204
http://dx.doi.org/10.1038/s41586-019-1397-7