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Effects of pentoxifylline on whole blood IL‐2 and IFN‐gamma gene expression in normal dogs

BACKGROUND: Pentoxifylline (PTX) is a methylxanthine phosphodiesterase inhibitor that is used as a hemorrheologic and anti‐inflammatory agent in veterinary and human medicine. In human studies, PTX has been shown to decrease T‐cell production of cytokines such as IL‐2 and IFN‐γ. A RT‐qPCR assay to m...

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Detalles Bibliográficos
Autores principales: Kummari, Evangel, Gibbs, Andres, Riggs, Caitlin, Fellman, Claire, Stokes, John, Thomason, John, Wills, Robert, Mackin, Andrew, Archer, Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036308/
https://www.ncbi.nlm.nih.gov/pubmed/31621209
http://dx.doi.org/10.1002/vms3.204