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α-catenin isoforms are regulated by glucose and involved in regulating insulin secretion in rat clonal β-cell models

The recent finding that β-catenin levels play an important rate-limiting role in processes regulating insulin secretion lead us to investigate whether its binding partner α-catenin also plays a role in this process. We find that levels of both α-E-catenin and α-N-catenin are rapidly up-regulated as...

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Detalles Bibliográficos
Autores principales: Dissanayake, Waruni C., Sorrenson, Brie, Lee, Kate L., Barre, Sandra, Shepherd, Peter R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036346/
https://www.ncbi.nlm.nih.gov/pubmed/32003420
http://dx.doi.org/10.1042/BCJ20190832