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Inhibition of EZH2 Attenuates Sorafenib Resistance by Targeting NOTCH1 Activation-Dependent Liver Cancer Stem Cells via NOTCH1-Related MicroRNAs in Hepatocellular Carcinoma()()

Acquired resistance and intrinsic to sorafenib therapy represents a major hurdle in improving the management of advanced hepatocellular carcinoma (HCC), which has been recently shown to be associated with the emergence of liver cancer stem cells (CSCs). However, it remains largely unknown whether an...

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Detalles Bibliográficos
Autores principales: Wang, Shanshan, Cai, Long, Zhang, Fengwei, Shang, Xuechai, Xiao, Rong, Zhou, Hongjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036423/
https://www.ncbi.nlm.nih.gov/pubmed/32092673
http://dx.doi.org/10.1016/j.tranon.2020.01.002