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Inhibition of EZH2 Attenuates Sorafenib Resistance by Targeting NOTCH1 Activation-Dependent Liver Cancer Stem Cells via NOTCH1-Related MicroRNAs in Hepatocellular Carcinoma()()
Acquired resistance and intrinsic to sorafenib therapy represents a major hurdle in improving the management of advanced hepatocellular carcinoma (HCC), which has been recently shown to be associated with the emergence of liver cancer stem cells (CSCs). However, it remains largely unknown whether an...
Autores principales: | Wang, Shanshan, Cai, Long, Zhang, Fengwei, Shang, Xuechai, Xiao, Rong, Zhou, Hongjuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036423/ https://www.ncbi.nlm.nih.gov/pubmed/32092673 http://dx.doi.org/10.1016/j.tranon.2020.01.002 |
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