A Novel Drug Delivery Carrier Comprised of Nimodipine Drug Solution and a Nanoemulsion: Preparation, Characterization, in vitro, and in vivo Studies

PURPOSE: Nimodipine (NIMO) is used clinically to treat ischemic damage resulting from subarachnoid hemorrhage. However, clinical application of NIMO is limited by poor aqueous solubility and low safety. To overcome these limitations, a novel two-vial NIMO-loaded nanoemulsion (NIMO-TNE) was designed...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Saixu, Huang, Zhiyong, Fu, Zhiqin, Shi, Yamin, Dai, Qi, Tang, Shuyan, Gu, Yongwei, Xu, Youfa, Chen, Jianming, Wu, Xin, Ren, Fuzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036601/
https://www.ncbi.nlm.nih.gov/pubmed/32110014
http://dx.doi.org/10.2147/IJN.S226591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036601/
https://www.ncbi.nlm.nih.gov/pubmed/32110014
http://dx.doi.org/10.2147/IJN.S226591

Ejemplares similares