Cargando…

A Novel Drug Delivery Carrier Comprised of Nimodipine Drug Solution and a Nanoemulsion: Preparation, Characterization, in vitro, and in vivo Studies

PURPOSE: Nimodipine (NIMO) is used clinically to treat ischemic damage resulting from subarachnoid hemorrhage. However, clinical application of NIMO is limited by poor aqueous solubility and low safety. To overcome these limitations, a novel two-vial NIMO-loaded nanoemulsion (NIMO-TNE) was designed...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Saixu, Huang, Zhiyong, Fu, Zhiqin, Shi, Yamin, Dai, Qi, Tang, Shuyan, Gu, Yongwei, Xu, Youfa, Chen, Jianming, Wu, Xin, Ren, Fuzheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036601/ https://www.ncbi.nlm.nih.gov/pubmed/32110014 http://dx.doi.org/10.2147/IJN.S226591

Ejemplares similares

Peptide T7-modified polypeptide with disulfide bonds for targeted delivery of plasmid DNA for gene therapy of prostate cancer
por: Lu, Yue, et al.
Publicado: (2018)

Nimodipine Reappraised: An Old Drug with a Future
por: Carlson, Andrew P., et al.
Publicado: (2020)

Emulsion-Based Multicompartment Vaginal Drug Carriers: From Nanoemulsions to Nanoemulgels
por: Smoleński, Michał, et al.
Publicado: (2021)

Design of eudragit RL nanoparticles by nanoemulsion method as carriers for ophthalmic drug delivery of ketotifen fumarate
por: Soltani, Saieede, et al.
Publicado: (2016)

Nanoemulsions for “Nose-to-Brain” Drug Delivery
por: Bonferoni, Maria Cristina, et al.
Publicado: (2019)

Microemulsions and Nanoemulsions in Skin Drug Delivery
por: Souto, Eliana B., et al.
Publicado: (2022)

Cationic nanoemulsions as potential carriers for intracellular delivery
por: Khachane, P.V., et al.
Publicado: (2015)

The Effect of Nanoemulsion as a Carrier of Hydrophilic Compound for Transdermal Delivery
por: Tsai, Ming-Jun, et al.
Publicado: (2014)

Facile methodology of nanoemulsion preparation using oily polymer for the delivery of poorly soluble drugs
por: Wik, Johanna, et al.
Publicado: (2019)

Nanoemulsion: an advanced mode of drug delivery system
por: Jaiswal, Manjit, et al.
Publicado: (2014)

The glyconanoparticle as carrier for drug delivery
por: Zhang, Xueqin, et al.
Publicado: (2018)

Dasatinib Nanoemulsion and Nanocrystal for Enhanced Oral Drug Delivery
por: Wang, Chuanqi, et al.
Publicado: (2022)

Preparation and evaluation of a Rubropunctatin-loaded liposome anticancer drug carrier
por: Xu, Dongling, et al.
Publicado: (2020)

Preparation and use of nanogels as carriers of drugs
por: Li, Cuixia, et al.
Publicado: (2021)

Oral Drug Delivery Systems Comprising Altered Geometric Configurations for Controlled Drug Delivery
por: Moodley, Kovanya, et al.
Publicado: (2011)

Preparation of amphiphilic magnetic polyvinyl alcohol targeted drug carrier and drug delivery research
por: Wang, Yazhen, et al.
Publicado: (2020)

Improving Drug Delivery for Alzheimer’s Disease Through Nose-to-Brain Delivery Using Nanoemulsions, Nanostructured Lipid Carriers (NLC) and in situ Hydrogels
por: Cunha, Sara, et al.
Publicado: (2021)

Application of hyaluronic acid as carriers in drug delivery
por: Huang, Gangliang, et al.
Publicado: (2018)

Techniques for Formulation of Nanoemulsion Drug Delivery System: A Review
por: Kumar, Manish, et al.
Publicado: (2019)

Improving Drug Delivery on Candida Albicans Using Geraniol Nanoemulsion
por: Silva Pontes, Cristiano, et al.
Publicado: (2023)

Multiple Porous Synthetic Bone Graft Comprising EngineeredMicro-Channel for Drug Carrier and Bone Regeneration
por: Bae, Chun-Sik, et al.
Publicado: (2021)

Preparation and drug delivery of dextran-drug complex
por: Huang, Shiyu, et al.
Publicado: (2019)

The Role of Solute Carrier Transporters in Efficient Anticancer Drug Delivery and Therapy
por: Puris, Elena, et al.
Publicado: (2023)

Role of solute carriers in response to anticancer drugs
por: Li, Qing, et al.
Publicado: (2014)

The ascension of nanosponges as a drug delivery carrier: preparation, characterization, and applications
por: Tiwari, Kartik, et al.
Publicado: (2022)

Preparation and characterization of nimodipine-loaded nanostructured lipid systems for enhanced solubility and bioavailability
por: Teng, Zaijin, et al.
Publicado: (2018)

Preparation and application of functionalized nano drug carriers
por: Gong, Rudong, et al.
Publicado: (2016)

Preparation and in vitro and in vivo Study of Asiaticoside-Loaded Nanoemulsions and Nanoemulsions-Based Gels for Transdermal Delivery
por: Li, Huimin, et al.
Publicado: (2020)

Ultrasound-Induced Release of Nimodipine from Drug-Loaded Block Copolymer Micelles: In Vivo Analysis
por: Döring, Katja, et al.
Publicado: (2022)

Nanoemulsions as novel nanocarrieres for drug delivery across the skin: In-vitro, in-vivo evaluation of miconazole nanoemulsions for treatment of Candidiasis albicans
por: Farooq, Umar, et al.
Publicado: (2021)

Nanoemulsion and Solid Nanoemulsion for Improving Oral Delivery of a Breast Cancer Drug: Formulation, Evaluation, and a Comparison Study
por: Tarik Alhamdany, Anas, et al.
Publicado: (2021)

Successfully Improving Ocular Drug Delivery Using the Cationic Nanoemulsion, Novasorb
por: Lallemand, Frederic, et al.
Publicado: (2012)

Nanoemulsion based Intranasal Delivery of Antimigraine Drugs for Nose to Brain Targeting
por: Bhanushali, R. S., et al.
Publicado: (2009)

Nanoemulsion as a Platform for Iontophoretic Delivery of Lipophilic Drugs in Skin Tumors
por: Dalmolin, Luciana Facco, et al.
Publicado: (2018)

Delivery of Hydrophobic Drugs to the Posterior Ocular Region by Gel-in-Water Nanoemulsion
por: Fardous, Jannatul, et al.
Publicado: (2022)

Charge-Converting Nanoemulsions as Promising Retinal Drug and Gene Delivery Systems
por: Nguyen Le, Nguyet-Minh, et al.
Publicado: (2022)

Preparation of Hybrid Alginate-Chitosan Aerogel as Potential Carriers for Pulmonary Drug Delivery
por: Alnaief, Mohammad, et al.
Publicado: (2020)

Nimodipine-Loaded Pluronic(®) Block Copolymer Micelles: Preparation, Characterization, In-vitro and In-vivo Studies
por: Sotoudegan, Farzaneh, et al.
Publicado: (2016)

Development and characterization of a novel nanoemulsion drug-delivery system for potential application in oral delivery of protein drugs
por: Sun, Hongwu, et al.
Publicado: (2012)

Nanoemulsions as a Promising Carrier for Topical Delivery of Etodolac: Formulation Development and Characterization
por: Özdemir, Samet, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_obkph8inkmq6sq38nehj7i5l4q