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MicroRNA-20b Promotes Cardiac Hypertrophy by the Inhibition of Mitofusin 2-Mediated Inter-organelle Ca(2+) Cross-Talk

MicroRNA (miRNA) and mitofusin-2 (Mfn2) are important in the development of cardiac hypertrophy, but the target relationship and mechanism associated with Ca(2+) handling between SR and mitochondria under hypertrophic condition is not established. Mfn2 expression, Mfn2-mediated interorganelle Ca(2+)...

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Detalles Bibliográficos
Autores principales: Qiu, Yue, Cheng, Rongchao, Liang, Chaoqi, Yao, Yuan, Zhang, Wenhao, Zhang, Jie, Zhang, Mingyu, Li, Baiyan, Xu, Chaoqian, Zhang, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036712/
https://www.ncbi.nlm.nih.gov/pubmed/32160705
http://dx.doi.org/10.1016/j.omtn.2020.01.017