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The Clustering of mApoE Anti-Amyloidogenic Peptide on Nanoparticle Surface Does Not Alter Its Performance in Controlling Beta-Amyloid Aggregation

The deposition of amyloid-β (Aβ) plaques in the brain is a significant pathological signature of Alzheimer’s disease, correlating with synaptic dysfunction and neurodegeneration. Several compounds, peptides, or drugs have been designed to redirect or stop Aβ aggregation. Among them, the trideca-pept...

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Detalles Bibliográficos
Autores principales: Corti, Roberta, Cox, Alysia, Cassina, Valeria, Nardo, Luca, Salerno, Domenico, Marrano, Claudia Adriana, Missana, Natalia, Andreozzi, Patrizia, Silva, Paulo Jacob, Stellacci, Francesco, Dal Magro, Roberta, Re, Francesca, Mantegazza, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036774/
https://www.ncbi.nlm.nih.gov/pubmed/32033502
http://dx.doi.org/10.3390/ijms21031066