Synthesis of New Cisplatin Derivatives from Bile Acids

A series of bile acid derived 1,2- and 1,3-diamines as well as their platinum(II) complexes were designed and synthesized in hope to get a highly cytotoxic compound by the combination of two bioactive moieties. All complexes obtained were subjected to cytotoxicity assays in vitro and some hybrid mol...

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Detalles Bibliográficos
Autores principales: Seroka, Barbara, Łotowski, Zenon, Hryniewicka, Agnieszka, Rárová, Lucie, R. Sicinski, Rafal, M. Tomkiel, Aneta, W. Morzycki, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036801/
https://www.ncbi.nlm.nih.gov/pubmed/32033039
http://dx.doi.org/10.3390/molecules25030655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036801/
https://www.ncbi.nlm.nih.gov/pubmed/32033039
http://dx.doi.org/10.3390/molecules25030655

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