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Synthesis of New Cisplatin Derivatives from Bile Acids
A series of bile acid derived 1,2- and 1,3-diamines as well as their platinum(II) complexes were designed and synthesized in hope to get a highly cytotoxic compound by the combination of two bioactive moieties. All complexes obtained were subjected to cytotoxicity assays in vitro and some hybrid mol...
Autores principales: | Seroka, Barbara, Łotowski, Zenon, Hryniewicka, Agnieszka, Rárová, Lucie, R. Sicinski, Rafal, M. Tomkiel, Aneta, W. Morzycki, Jacek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036801/ https://www.ncbi.nlm.nih.gov/pubmed/32033039 http://dx.doi.org/10.3390/molecules25030655 |
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