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Low Molecular Weight Hyaluronan Induces an Inflammatory Response in Ovarian Stromal Cells and Impairs Gamete Development In Vitro

The ovarian stroma, the microenvironment in which female gametes grow and mature, becomes inflamed and fibrotic with age. Hyaluronan is a major component of the ovarian extracellular matrix (ECM), and in other aging tissues, accumulation of low molecular weight (LMW) hyaluronan fragments can drive i...

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Detalles Bibliográficos
Autores principales: Rowley, Jennifer E., Amargant, Farners, Zhou, Luhan T., Galligos, Anna, Simon, Leah E., Pritchard, Michele T., Duncan, Francesca E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036885/
https://www.ncbi.nlm.nih.gov/pubmed/32033185
http://dx.doi.org/10.3390/ijms21031036