Cargando…

Design, Synthesis, Molecular Modelling and Anticancer Activities of New Fused Phenanthrolines

Three series of fused pyrrolophenanthroline derivatives were designed as analogues of phenstatin and synthesized in two steps starting with 1,7-phenanthroline, 4,7-phenanthroline and 1,10-phenanthroline, respectively. Two (Compounds 8a and 11c) of the four compounds tested against a panel of sixty h...

Descripción completa

Detalles Bibliográficos
Autores principales: Al Matarneh, Cristina Maria, Amarandi, Roxana Maria, Craciun, Anda Mihaela, Mangalagiu, Ionel I., Zbancioc, Gheorghita, Danac, Ramona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036904/
https://www.ncbi.nlm.nih.gov/pubmed/31991806
http://dx.doi.org/10.3390/molecules25030527