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New Modified Deoxythymine with Dibranched Tetraethylene Glycol Stabilizes G-Quadruplex Structures

Methods for stabilizing G-quadruplex formation is a promising therapeutic approach for cancer treatment and other biomedical applications because stable G-quadruplexes efficiently inhibit biological reactions. Oligo and polyethylene glycols are promising biocompatible compounds, and we have shown th...

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Detalles Bibliográficos
Autores principales: Tateishi-Karimata, Hisae, Ohyama, Tatsuya, Muraoka, Takahiro, Tanaka, Shigenori, Kinbara, Kazushi, Sugimoto, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036917/
https://www.ncbi.nlm.nih.gov/pubmed/32041318
http://dx.doi.org/10.3390/molecules25030705